Fig 10.

Distribution of Trp residues within the various domain regions of Pmp proteins. A total of 63 intact Pmps are displayed and color coded with respect to domain regions as defined across the top. These Pmps are from five genomes: Chlamydophila caviae GPIC (CCA), Chlamydophila abortus S26/3 (CAB), Chlamydophila pneumoniae AR39 (CP), Chlamydia trachomatis D/UW-3/CX (CT), and Chlamydia muridarum Nigg (TC). CAB267 and CCA00275 were eliminated from Fig. 10 because a lack of the Pmp_M domain and extremely short N-terminal domains probably rules out functional competence. Likewise, CP0301 was eliminated from the sequence collection owing to the complete absence of an autotransporter domain. The positions of individual Trp residues are indicated by black vertical lines. Pmp families defined by Grimwood and Stephens (45) are shown with brackets on the left margin. The initial set of cohesion groups obtained using cohesion group analysis (16, 74) is shown by green vertical lines at the left, and orphan sequences are depicted by solid red circles. The membership of the final six cohesion groups obtained is indicated by the four groups and two orphans, as separated by gaps along the right margin.