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. 2012 Jun;76(2):405–443. doi: 10.1128/MMBR.05013-11

Fig 11.

Fig 11

Methylerythritol phosphate pathway of isoprenoid biosynthesis. The key enzyme (IspE) which dictates MEC accumulation is highlighted in yellow, as are the key high-energy substrates CTP and ATP. The high Trp content of IspE, expressed as the p/P Trp ratio, is also highlighted.