Table 5.
Genomic comparison of proteins relevant to KDOa
| Organism | Genomic GC% | Proteomic % Trp | KdtA |
KdsA |
KdsB |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of Trp residues | Protein length (aa) | p/P Trp ratio | No. of Trp residues | Protein length (aa) | p/P Trp ratio | No. of Trp residues | Protein length (aa) | p/P Trp ratio | |||
| Blochmannia pennsylvanicus BPEN | 29.56 | 1.65 | 6 | 427 | 0.85 | 0 | 284 | 0.00 | 3 | 262 | 0.69 |
| Campylobacter jejuni jejuni NCTC 11168 | 30.55 | 0.65 | 3 | 385 | 1.20 | 0 | 271 | 0.00 | 0 | 239 | 0.00 |
| “Candidatus Protochlamydia amoebophila” UWE25 | 34.72 | 1.13 | 7 | 417 | 1.49 | 1 | 275 | 0.32 | 2 | 259 | 0.68 |
| Bartonella henselae Houston-1 | 38.23 | 1.06 | 7 | 440 | 1.50 | 1 | 279 | 0.34 | 0 | 243 | 0.00 |
| Legionella pneumophila Paris | 38.37 | 1.15 | 6 | 419 | 1.25 | 2 | 274 | 0.63 | 3 | 250 | 1.04 |
| Helicobacter pylori 26695 | 38.87 | 0.7 | 5 | 393 | 1.82 | 1 | 276 | 0.52 | 0 | 243 | 0.00 |
| Chlamydophila caviae GPIC | 39.19 | 0.95 | 10 | 434 | 2.43 | 3 | 269 | 1.17 | 1 | 254 | 0.41 |
| Chlamydophila felis Fe/C-56 | 39.34 | 0.95 | 9 | 434 | 2.18 | 3 | 269 | 1.17 | 1 | 254 | 0.41 |
| Chlamydophila abortus S26/3 | 39.87 | 0.96 | 9 | 411 | 2.28 | 3 | 269 | 1.16 | 1 | 254 | 0.41 |
| Chlamydia muridarum Nigg | 40.3 | 0.97 | 11 | 430 | 2.64 | 3 | 269 | 1.15 | 1 | 275 | 0.37 |
| Chlamydophila pneumoniae CWL029 | 40.58 | 1.01 | 8 | 437 | 1.81 | 3 | 269 | 1.10 | 1 | 254 | 0.39 |
| Chlamydia trachomatis D/UW-3/CX | 41.31 | 0.95 | 11 | 431 | 2.69 | 3 | 269 | 1.17 | 1 | 254 | 0.41 |
| Coxiella burnetii RSA 493 | 42.6 | 1.21 | 5 | 424 | 0.97 | 3 | 280 | 0.89 | 3 | 249 | 1.00 |
| Aquifex aeolicus VF5 | 43.3 | 0.93 | 3 | 353 | 0.91 | 3 | 267 | 1.21 | 1 | 234 | 0.46 |
| Chlorobium chlorochromatii CaD3 | 44.28 | 1.01 | 5 | 436 | 1.14 | 0 | 272 | 0.00 | 2 | 248 | 0.80 |
| Porphyromonas gingivalis W83 | 48.29 | 1.03 | 6 | 412 | 1.41 | 0 | 272 | 0.00 | 2 | 254 | 0.76 |
| Escherichia coli K-12 | 50.73 | 1.52 | 6 | 425 | 0.93 | 0 | 284 | 0.00 | 3 | 248 | 0.80 |
| Neisseria meningitidis Z2491 | 51.81 | 1.19 | 9 | 423 | 1.79 | 0 | 280 | 0.00 | 1 | 253 | 0.33 |
| Brucella suis 1330 | 57.25 | 1.21 | 6 | 446 | 1.11 | 1 | 277 | 0.30 | 0 | 251 | 0.00 |
| Agrobacterium tumefaciens C58 (Cereon) | 59.04 | 1.25 | 7 | 440 | 1.27 | 1 | 282 | 0.28 | 0 | 251 | 0.00 |
| Nitrobacter hamburgensis X14 | 61.62 | 1.35 | 4 | 434 | 0.68 | 1 | 287 | 0.26 | 0 | 258 | 0.00 |
| Rhodopseudomonas palustris BisB18 | 64.96 | 1.23 | 4 | 434 | 0.75 | 1 | 296 | 0.27 | 1 | 245 | 0.33 |
| Pseudomonas aeruginosa UCBPP-PA14 | 66.29 | 1.49 | 9 | 425 | 1.42 | 0 | 281 | 0.00 | 5 | 254 | 1.32 |
a
Enzyme abbreviations: KdtA, KDO transferase; KdsA, KDOP (2-keto-3-deoxy-d-manno-octulosonate-8-P) synthase; KdsB, CMP-KDO synthetase.