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. 2012 Jun;32(12):2183–2195. doi: 10.1128/MCB.00320-12

Table 1.

Proteins associated with TβRI in transformed cells with a known function in RNA posttranscriptional regulationa

Symbol Entrez name Location Type(s) Function annotation
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 Nucleus Enzyme rRNA processing
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 Nucleus Enzyme RNA modification, unwinding, and processing
DDX21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 Nucleus Enzyme RNA modification and unwinding
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 Nucleus Enzyme RNA modification and unwinding
DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 Nucleus Enzyme RNA modification and processing
EIF4A1 Eukaryotic translation initiation factor 4A, isoform 1 Cytoplasm Translation regulator mRNA binding, unwinding, and modification
FBL Fibrillarin Nucleus Other rRNA processing
HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1 Nucleus Other RNA modification, processing, and splicing
HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 (2H9) Nucleus Other RNA modification, processing, and splicing
HNRNPR Heterogeneous nuclear ribonucleoprotein R Nucleus Other RNA modification and processing
HNRNPL Heterogeneous nuclear ribonucleoprotein L Nucleus Other RNA modification, processing, and splicing
HNRNPM Heterogeneous nuclear ribonucleoprotein M Plasma membrane Transmembrane receptor RNA splicing
NPM1 Nucleophosmin (nucleolar phosphoprotein B23, numatrin) Nucleus Transcription regulator rRNA processing
SF3B3 Splicing factor 3b, subunit 3, 130 kDa Nucleus Other RNA modification, processing, and splicing
SYNCRIP Synaptotagmin binding, cytoplasmic RNA interacting protein Nucleus Other RNA modification, processing, and splicing
WDR43 WD repeat domain 43 Nucleus Other rRNA processing
a

Proteins associate with TβRI only in MCF10A/HER2 and MDA-MB-231 cells and not in MCF10A cells.