Table 1. Action profile of ion channel inhibitors, percentage of hyaluronan export and alteration of membrane potential at maximal inhibitory concentrations.
Channel Inhibitor | Kir | Na+ | Ca2+ | HA-inhibition (%) | Potential difference (mV) | |
KATP | KG | |||||
BaCl2 | + | + | 50 | −2 | ||
Glibenclamide | + | 50 | 5 | |||
Verapamil | + | 20 | 0 | |||
Ropivacain | + | + | 80 | 18 | ||
Amiloride | + | 20 | 6 |