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. 2012 Jun 11;7(6):e38985. doi: 10.1371/journal.pone.0038985

Table 2. Periods of retinal Per1::luc or PER2::LUC rhythms in mice of different genotypes.

Gene Genotype Period (h; Mean ± SEM) P value Statistical analysis Sample number
Per1 Per1+/+ 24.10±0.17 (b) Nonparametric Mann-Whitney U test 10
Per1+/− 23.27±0.06 (a) P<0.001 12
Per1−/− Arrythmic N/A 12
Per2 Per2+/+ 23.67±0.15 One-way ANOVA withFisher’s LSD post hoctest 13
Per2+/− 23.28±0.14 P>0.05 16
Per2−/− 23.19±0.30 P>0.05 10
Per3 Per3+/+ 24.40±0.19 (c) NonparametricKruskal-Wallis testfollowed by Dunnett's T3 post hoc test 12
Per3+/− 23.00±0.02 (b) P<0.001 10
Per3−/− 22.21±0.06 (a) P<0.001 10
Cry1 & Cry2 Cry1+/+Cry2+/+ 23.81±0.05 (c) NonparametricKruskal-Wallis testfollowed by Dunnett'sT3 post hoc test 10
Cry1+/−Cry2+/+ 23.16±0.08 (b) P<0.05 8
Cry1−/−Cry2+/+ 21.39±0.19 (a) P<0.001 14
Cry1+/+Cry2+/− 24.59±0.10 (d) P<0.05 10
Cry1+/−Cry2+/− 23.72±0.15 (bc) P>0.05 13
Cry1−/−Cry2+/− Arrhythmic N/A 20
Cry1+/+Cry2−/− 25.25±0.30 (d) P<0.05 12
Cry1+/−Cry2−/− 27.62±0.06 (e) P<0.001 22
Cry1−/−Cry2−/− Arrythmic N/A 14
Clock Clock+/+ 23.71±0.06 (a) Independent samples t-test 10
Clock+/− 24.27±0.10 (b) P<0.001 10
Clock−/− Arrythmic N/A 8

Letters indicate significant difference with a<b<c<d<e. P values are for comparisons to wild-type mice. A minimum of three animals were sampled for each genotype.