Table 4. Periods of SCN Per1::luc or PER2::LUC rhythms in mice of different genotypes.
| Gene | Genotype | Period (h; Mean ± SEM) | P value | Statistical analysis | Sample number |
| Per1 | Per1+/+ | 24.27±0.03 (a) | Nonparametric Kruskal-Wallis test followed byDunnett's T3 post hoc test | 3 | |
| Per1+/− | 24.75±0.12 (b) | P<0.05 | 6 | ||
| Per1−/− | 26.18±0.09* (c) | P<0.001 | 4 | ||
| Per2 | Per2+/+ | 23.97±0.09 (c) | One-way ANOVA withFisher’s LSD post hoctest | 3 | |
| Per2+/− | 23.75±0.03 (b) | P<0.05 | 4 | ||
| Per2−/− | 22.80±0.06 (a) | P<0.001 | 3 | ||
| Per3 | Per3+/+ | 23.97±0.07 | One-way ANOVA withFisher’s LSD post hoctest | 3 | |
| Per3+/− | 24.10±0.17 | P>0.05 | 3 | ||
| Per3−/− | 24.26±0.22 | P>0.05 | 3 | ||
| Cry1 & Cry2 | Cry1+/+Cry2+/+ | 24.14±0.11 (bc) | One-way ANOVA withthe Tukey HSD posthoc test | 5 | |
| Cry1+/−Cry2+/+ | 23.90±0.21 (b) | P>0.05 | 4 | ||
| Cry1−/−Cry2+/+ | 22.37±0.12 (a) | P<0.05 | 3 | ||
| Cry1+/+Cry2+/− | 24.65±0.07 (c) | P>0.05 | 6 | ||
| Cry1+/−Cry2+/− | 24.87±0.20 (cd) | P>0.05 | 6 | ||
| Cry1−/−Cry2+/− | 21.75±0.13 (a) | P<0.01 | 4 | ||
| Cry1+/+Cry2−/− | 25.45±0.32 (d) | P<0.05 | 3 | ||
| Cry1+/−Cry2−/− | 25.53±0.12 (d) | P<0.05 | 4 | ||
| Cry1−/−Cry2−/− | Arrythmic | N/A | 4 | ||
| Clock | Clock+/+ | 24.20±0.06 (b) | One-way ANOVA withFisher’s LSD post hoctest | 3 | |
| Clock+/− | 24.36±0.16 (b) | P>0.05 | 5 | ||
| Clock−/− | 23.30±0.12 (a) | P<0.01 | 3 |
Letters indicate significant difference with a<b<c<d. P values are for comparisons to wild-type mice. A minimum of three animals were sampled for each genotype. “*”, the period of PER2::LUC rhythms in Per1−/− SCN explants was calculated after media change.