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. Author manuscript; available in PMC: 2012 Jun 12.
Published in final edited form as: Psychopharmacology (Berl). 2007 Dec 27;197(1):157–168. doi: 10.1007/s00213-007-1020-8

TABLE 3.

Summary of Results

THC Lofexidine THC/Lofexidine
Marijuana Withdrawal
  • ⇑

    Good Drug Effect, Mellow, Talkative, Irritable

  • ⇑

    Capsule Strength, Liking, Take again

  • ⇑

    Food intake

  • ⇑

    Psychomotor task performance
  • ⇑

    Sedation

  • ⇑

    Capsule Strength

  • ⇑

    Sleep (objective and subjective)
  • ⇑

    Good Drug Effect, Sedated

  • ⇑

    Capsule Strength

  • ⇑

    Sleep (objective and subjective)

  • ⇑

    Psychomotor task performance
  • ⇓

    Restless, Chills

  • ⇓

    Sleep (objective)

  • ⇓

    Time spent Talking
  • ⇓

    Restless, Chills, Upset Stomach

  • ⇓

    Food intake

  • ⇓

    Time spent Talking
  • ⇓

    Restless, Chills, Upset Stomach, Marijuana Craving, Cigarette Craving, Social, Talkative

  • ⇓

    Cigarette smoking

  • ⇓

    Time spent Talking
  • ⇑⇓

    Psychomotor task performance

Marijuana Relapse No Change Decrease Decrease