Table 2a.
Result of univariate analysis showing Talairach coordinates for local maxima regions in each speaking task where voxel clusters ( ≥ 10; p < .05) were significantly more activated for PWS group than for CONT group (PWS>CONT Group) and where regions were significantly more activated in CONT group than PWS group (CONT>PWS Group).
| PWS>CONT Group | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Monologue vs ECR | Oral Reading vs ECR | ||||||||
| Lobe | Region | X | Y | Z | Clust | X | Y | Z | Clust |
| Frontal | |||||||||
| Left | SMA (6) | -9 | -11 | 61* | |||||
| Precentral gyrus (4) | -55 | -20 | 33* | 30 | |||||
| Right | SMA (6) | 4 | -3 | 58* | 434 | 6 | -2 | 60* | 43 |
| Precentral gyrus (4) | 5 2 | -13 | 38* | 60 | |||||
| Parietal | |||||||||
| Right | Post central gyrus (3) | 52 | -17 | 38 | 24 | ||||
| Occipital | |||||||||
| Left | Cuneus (17) | -11 | -78 | 13 | 25 | ||||
| Cuneus (18) | -7 | -75 | 26* | 24 | |||||
| Cerebellum | |||||||||
| Right | Lobule V | 5 | -64 | -36 | 52 | ||||
| Lobule VI | 36 | -60 | -19* | 39 | |||||
| CONT>PWS Group | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Monologue vs ECR | Oral Reading vs ECR | ||||||||
| X | Y | Z | Clust | X | Y | Z | Clust | ||
| Sub-lobar | |||||||||
| Left | Claustrum | -27 | -9 | 19 | 58 | ||||
| Insula (13) | -29 | -11 | 21 | 70 | |||||
| Insula (13) | -27 | -30 | 23 | 31 | |||||
| Caudate | -22 | -17 | 24 | ||||||
| Subthalamic nucleus | -16 | -12 | -4 | 15 | |||||
| Right | Globus pallidus | 16 | -2 | 4 | 14 | ||||
| Occipital | |||||||||
| Right | Cuneus (19) | 9 | -87 | 27 | 10 | ||||
| Cuneus (18) | 10 | -85 | 23 | ||||||
| Brainstem | |||||||||
| Left | Red nucleus | -5 | -23 | -11 | 26 | ||||
| Cerebellum | |||||||||
| Left | Lobule V | -8 | -64 | -18 | |||||
| Lobule VI | -63 | -9 | 152 | ||||||
| Lobule VI | -25 | -48 | -37 | 31 | |||||
| Lobule VI | -32 | -58 | -14 | 41 | |||||
*
Submaxima coordinates are italicized. Regional coordinates with correspond to those identified in Brown et al's (2005) ALE analysis as stutter-related. All activations were derived after a correction was made for the number of syllables (i.e., speaking rate) produced per scan.