Table 2.
Association of rs1202524 and 1202529 with Type I endometrial cancer, for all participants and by ethnicity
Population | SNP | N | Frequency | OR (95% CI) | P | |||
---|---|---|---|---|---|---|---|---|
| ||||||||
Cases | Controls | Cases | Controls | Heterzygotes | Homozygotes | |||
All women: Type I endometrial cancer cases vs controls | ||||||||
rs1202524 | 7558 | 16557 | 0.27 | 0.25 | 1.11(1.04– 1.18) | 1.21(1.08– 1.35) | 2.4E-05 | |
rs1202529 | 7546 | 16541 | 0.27 | 0.25 | 1.11(1.04– 1.18) | 1.19(1.07– 1.33) | 3.2E-05 | |
Asian women: Type I endometrial cancer cases vs controls | ||||||||
rs1202524 | 1689 | 3829 | 0.11 | 0.10 | 1.22(1.05– 1.42) | 1.60(0.86– 2.96) | 3.0E-03 | |
rs1202529 | 1681 | 3812 | 0.11 | 0.10 | 1.22(1.05– 1.42) | 1.45(0.78– 2.69) | 4.6E-03 | |
European-ancestry women: Type I endometrial cancer cases vs controls | ||||||||
rs1202524 | 6646 | 11797 | 0.32 | 0.31 | 1.07(1.00–1.15) | 1.18(1.06–1.32) | 1.7E-03 | |
rs1202529 | 6641 | 11796 | 0.32 | 0.31 | 1.07(1.00–1.15) | 1.17(1.05–1.31) | 2.2E-03 |