Skip to main content
. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Biochem Pharmacol. 2012 May 10;84(3):352–365. doi: 10.1016/j.bcp.2012.04.022

Figure 7.

Figure 7

The effects of α7-selective agonists on zebrafish nAChR. Three agents previously characterized as being selective activators of human α7 nAChR [32] were tested at the concentrations indicated for their ability to either activate zebrafish nAChR (A) or inhibit the ACh-evoked responses of the zebrafish nAChR (B). The ACh control concentrations used for the inhibition studies were 100 µM, 30 µM, 30 µM, 30 µM, and 60 µM for the α3β4, α1β1bεδ, α2β2, α4β2, and α7 receptors, respectively. Each column represents the average ± SEM of responses from at least four oocytes.