Skip to main content
. 2012 Mar;165(5):1467–1475. doi: 10.1111/j.1476-5381.2011.01626.x

Figure 6.

Figure 6

Downstream Rho kinase signalling in oocytes with mutant TASK1 channels and ETA or ETB receptors. Mutant TASK1 channels lacking the consensus sites for Rho kinase phosphorylation (TASK1-S336A; TASK1-S393A) were generated. Effects of ET-1 (20 nM) on mutant TASK1 channels in the presence of ETA receptors (A) or ETB receptors (B) are displayed. In each panel, control recordings (30 min) and the effect of ET-1 (20 nM) on TASK1 wild type channels are shown for comparison. Data are given as mean ± SEM; ***P < 0.001 versus wild type TASK1.