Table 3.
Clinical Characteristics, New Onset of Comorbidities, and Treatment for Lifetime BP with versus without Anxiety Disorders since Wave 1
| BP with Anxiety N=725; %=2.09 |
BP without Anxiety N=875; %=2.38 |
|||||||
|---|---|---|---|---|---|---|---|---|
| % or MEAN | SE | % or MEAN | SE | AOR* | 95%CI* | t*/Wa ld Chi Sq* | p-value* | |
| Clinical Characteristics of BP | ||||||||
| BP subtype | ||||||||
| BP-I | 78.03 | 1.88 | 70.54 | 1.90 | 1.37 | 1.03–1.83 | 4.95 | 0.03 |
| BP-II | 21.97 | 1.88 | 29.46 | 1.90 | 1(ref) | |||
| Any MDE | 54.58 | 2.23 | 39.19 | 2.05 | 1.39 | 1.33–2.24 | 2.25 | <0.0001 |
| Number of MDE | 3.37 | 0.24 | 2.76 | 0.16 | 1.45 | 0.03 | ||
| Length of MDE (week)** | 11.85 | 1.20 | 9.94 | 1.12 | 0.2 | |||
| Recovery from depression | 71.78 | 4.92 | 84.60 | 4.64 | 0.47 | 0.18–1.19 | 0.1 | |
| Any manic/hypomanic episodes | 41.46 | 2.30 | 29.5 | 1.99 | 1.83 | 1.35–2.48 | 2.59 | <0.0001 |
| Number of manic/hypomanic episodes | 3.63 | 0.25 | 2.72 | 0.29 | 1.02 | 0.01 | ||
| Length of mania (week)** | 6.30 | 0.98 | 5.31 | 5.31 | 0.3 | |||
| Recovery from mania | 73.64 | 4.56 | 79.68 | 4.73 | 0.71 | 0.33–1.52 | 0.4 | |
| Attempted suicide | 8.57 | 1.84 | 6.08 | 1.65 | 1.56 | 0.74–3.30 | 0.2 | |
| Suicidal ideation | 35.67 | 2.80 | 25.74 | 3.08 | 1.66 | 1.07–2.57 | 0.02 | |
| Lifetime suicide attempt | 27.85 | 2.68 | 18.74 | 2.61 | 1.64 | 1.05–2.56 | 0.5 | 0.03 |
| Earliest suicide attempt | 23.66 | 1.33 | 24.12 | 2.31 | 0.24 | 0.6 | ||
| Recent suicide attempt | 30.84 | 1.85 | 31.19 | 2.29 | 0.8 | |||
| New Onset of Comorbidites | ||||||||
| Any Anxiety Disorders | 16.89 | 1.63 | 16.08 | 1.50 | 1.04 | 0.74–1.48 | 0.8 | |
| PANIC | 11.99 | 2.11 | 4.27 | 1.15 | 3.37 | 0.99–5.70 | <0.001 | |
| SAD | 9.25 | 1.93 | 6.48 | 0.97 | 1.64 | 0.92–2.94 | 0.09 | |
| GAD | 12.63 | 1.76 | 9.35 | 0.69 | 1.34 | 0.88–2.06 | 0.2 | |
| Alcohol Use Disorders | 12.59 | 2.06 | 20.15 | 2.05 | 0.76 | 0.49–1.17 | 0.2 | |
| Drug Use Disorders | 9.46 | 1.60 | 6.74 | 1.11 | 1.76 | 1.07–2.88 | 0.02 | |
| Nicotine Dependence | 6.95 | 1.85 | 7.81 | 1.34 | 0.98 | 0.50–1.94 | 0.9 | |
| Treatment for BP | ||||||||
| Counselor for MDE | 51.61 | 3.09 | 32.42 | 3.18 | 2.01 | 1.35–3.00 | 0.0005 | |
| Hospitalized for MDE | 13.25 | 2.15 | 7.92 | 1.80 | 1.75 | 0.94–3.29 | 0.07 | |
| Emergency room for MDE | 15.21 | 2.40 | 7.29 | 1.72 | 2.29 | 1.21–4.34 | 0.01 | |
| Medication for MDE | 51.90 | 3.10 | 34.27 | 3.36 | 1.87 | 1.24–2.84 | 0.003 | |
| Sought any treatment for MDE | 59.79 | 3.03 | 39.73 | 3.25 | 2.05 | 1.38–3.06 | 0.0003 | |
| Counselor for mania/hypomania | 33.66 | 3.59 | 17.78 | 3.02 | 2.02 | 1.08–3.78 | 0.03 | |
| Hospitalized for mania/hypomania | 6.41 | 2.01 | 4.73 | 1.45 | 1.56 | 0.57–4.30 | 0.4 | |
| Emergency room for mania/hypomania | 6.45 | 1.96 | 3.93 | 1.33 | 1.86 | 3.06–3.78 | 0.3 | |
| Medication for mania/hypomania | 33.93 | 3.20 | 18.24 | 2.99 | 1.99 | 1.15–3.43 | 0.01 | |
| Sought any treatment for mania/hypomania | 40.94 | 3.44 | 22.92 | 3.40 | 2.04 | 1.18–3.56 | 0.01 | |
Abbreviations: BP=Bipolar Disorder, BP-I= Bipolar Disorder I, BP-II= Bipolar Disorder II. MDE=Major Depressive Episode, SAD=Separation Anxiety Disorder, GAD=Generalized Anxiety Disorder.
*
AOR is adjusted by age, gender, race and income;
**
longest duration