Figure 1.

Overview of chemokine receptors (vertical) and their ligands (horizontal). An open circle indicates the specific ligand binds to the receptor connected to it by a black line. From top to bottom: human chemokine receptors (XCR1 to CX3CR1), chemokine decoy receptors (D6 to CCX CKR) and viral chemokine receptors (US28 to U51). For reasons of clarity, this figure does not show differences in affinity or activity between ligands for the same receptor. For more detailed information on ligand properties, visit the website of The International Union of Basic and Clinical Pharmacology (IUPHAR) (Murphy et al., 2011).