Table 1.

Effect of F 16618 on coagulation and haemostasis in whole blood

	F 16618 (µM)		P value
	0	20
ROTEM-CT (s)	68 ± 2 (60–76)	71 ± 3 (61–82)	NS
ROTEM-CTF (s)	117 ± 9 (82–156)	117 ± 11 (78–167)	NS
ROTEM-MCF (mm)	56 ± 2 (49–67)	56 ± 2 (49–64)	NS
PFA collagen-ADP (s)	100 ± 8 (75–126)	99 ± 7 (80–125)	NS
PFA collagen-adrenaline (s)	126 ± 10 (105–166)	136 ± 14 (103–180)	NS

Clotting time (CT), clot formation time (CFT) and maximum clot firmness (MCF). All data are means ± SEM (range) of six separate experiments.