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. 2012 Mar;165(6):1836–1847. doi: 10.1111/j.1476-5381.2011.01672.x

Figure 1.

Figure 1

RT-PCR analysis of SLCO1B1 (encoding OATP1B1), UGT1A1 (encoding UGT1A1) and ABCC2 (encoding MRP2) mRNA expression in MDCK control cells (Co), single- (OATP1B1), double- (OATP1B1-UGT1A1, OATP1B1-MRP2) and triple-transfected cells (OATP1B1-UGT1A1-MRP2) used in this study. Real-time PCR analysis determining mRNA expression was repeated three times. All data are presented as mean ± SD. Statistical analyses were performed between the transfected cell lines among themselves. No expression of human SLCO1B1, UGT1A1 or ABCC2 mRNA could be detected in control cells (Co). Multiple comparisons were analysed by anova with subsequent Tukey–Kramer multiple comparison test. Pairwise comparisons were calculated by unpaired t-tests. **P < 0.01 versus MDCK-OATP1B1-UGT1A1 cells.