Table 1.
Species | Dose range (mg.kg−1) | R + V | Vomits | Episodes | Bouts | Kaolin consumption (g) |
---|---|---|---|---|---|---|
Human | 1–5 | n/a | n/a | n/a | 7 | n/a |
Dog | 1–5 | 138 | 13 | n/a | 13 | n/a |
Ferret | 6–10 | 134 | 16 | 37 | 17 | n/a |
Rat | 1–5 | n/a | n/a | n/a | n/a | 6 |
Cisplatin was administered i.v. or i.p.. The characteristics of the response induced by cisplatin were computed as the weighted average for all doses within the dose range, with data from 180 human patients, 476 dogs, 635 ferrets and 106 rats.