Table 2.
Serotype | CWPS-adsorbed titer | Non-adsorbed titer | ||||
---|---|---|---|---|---|---|
Al(OH)3 control | WCV-immunized | Fold-difference | Al(OH)3 control | WCV-immunized | Fold-difference | |
Clinical isolates | ||||||
3 | 65 | 670 | 10 | 55 | 1000 | 18 |
4 | 38 | 1700 | 45 | 45 | 2300 | 51 |
4 | 100 | 2000 | 20 | 120 | 2900 | 24 |
4 | 25 | 1500 | 60 | 88 | 3200 | 36 |
6B | 110 | 2500 | 23 | 125 | 3800 | 30 |
6B | 25 | 1500 | 60 | 90 | 2100 | 23 |
6B | 25 | 1600 | 64 | 92 | 3500 | 38 |
9V | 97 | 1800 | 19 | 120 | 3800 | 32 |
9V | 67 | 1300 | 19 | 110 | 3100 | 28 |
9V | 54 | 2200 | 41 | 46 | 3000 | 65 |
12F | 35 | 2100 | 60 | 39 | 3800 | 97 |
14 | 25 | 1400 | 56 | 90 | 2000 | 22 |
14 | 85 | 1800 | 21 | 90 | 2900 | 32 |
15B | 74 | 3600 | 49 | 110 | 6600 | 60 |
23F | 25 | 3400 | 140 | 100 | 5000 | 50 |
1 | 17 | 2200 | 130 | NA | NA | NA |
6B | 58 | 3000 | 52 | NA | NA | NA |
7C | 32 | 3300 | 100 | NA | NA | NA |
7F | 19 | 3000 | 160 | NA | NA | NA |
14 | 33 | 2300 | 70 | NA | NA | NA |
18C | 6 | 1800 | 300 | NA | NA | NA |
22F | 31 | 1600 | 52 | NA | NA | NA |
23F | 30 | 2300 | 77 | NA | NA | NA |
Isogenic TIGR4 strains TIGR4:Capsular Type | ||||||
TIGR4:1 | 70 | 2400 | 34 | 80 | 2900 | 36 |
TIGR4:2 | 88 | 2500 | 28 | 110 | 3300 | 30 |
TIGR4:3 | 78 | 3400 | 43 | 80 | 4000 | 50 |
TIGR4:4 | 85 | 3700 | 43 | 95 | 4200 | 44 |
TIGR4:5 | 80 | 2900 | 36 | 80 | 3400 | 43 |
TIGR4:6A | 105 | 2900 | 27 | 110 | 3100 | 28 |
TIGR4:6B | 100 | 3200 | 32 | 110 | 3700 | 34 |
TIGR4:7F | 80 | 2400 | 30 | 85 | 2800 | 33 |
TIGR4:8 | 100 | 3000 | 30 | 120 | 3400 | 28 |
TIGR4:9N | 100 | 3000 | 30 | 110 | 3400 | 31 |
TIGR4:9V | 100 | 2800 | 28 | 120 | 3500 | 29 |
TIGR4:10A | 100 | 2700 | 27 | 120 | 3800 | 32 |
TIGR4:11A | 120 | 3100 | 26 | 130 | 3900 | 30 |
TIGR4:12F | 70 | 2800 | 40 | 80 | 3200 | 40 |
TIGR4:14 | 78 | 3200 | 41 | 80 | 3400 | 43 |
TIGR4:18C | 90 | 2800 | 31 | 95 | 3100 | 33 |
TIGR4:19A | 90 | 3000 | 33 | 130 | 4400 | 34 |
TIGR4:19F | 110 | 3100 | 28 | 120 | 4200 | 35 |
TIGR4:23F | 100 | 2900 | 29 | 120 | 3400 | 28 |
TIGR4:35B | 80 | 3000 | 38 | 80 | 3200 | 40 |
TIGR4: Δcapsule | 100 | 4400 | 43 | 110 | 5000 | 45 |
NA – not assayed