Table 2.
Expression of ribosomal protein, transcription, and translation genes in three Diamond-Blackfan anemia (DBA) cell populations
| Cell population | Affymetrix identification | Gene symbol | Fold change | LocusLink |
|---|---|---|---|---|
| P | 222297_x_at | RPL18 | −2.27 | 604179 |
| 219762_s_at | RPL36 | −2.45 | 25873 | |
| 218128_at | NFYB | −2.25 | 4801 | |
| 202823_at | TCEB1 | −2.16 | 6921 | |
| 202163_s_at | CNOT8 | −2.42 | 9337 | |
| 206118_at | STAT4 | 2.53 | 6775 | |
| 203882_at | ISGF3G | 2.84 | 10379 | |
| E | 217336_at | RPS10 | −2.04 | 6204 |
| 208903_at | RPS28 | −2.08 | 6234 | |
| 217559_at | RPL10L | −6.66 | 140801 | |
| 219138_at | RPL14 | −13.8 | 9045 | |
| 222297_x_at | RPL18 | −2.10 | 6141 | |
| 216383_at | RPL18A | −3.14 | 6142 | |
| 200003_s_ | RPL28 | −2.06 | 6158 | |
| 213897_s_at | MRPL23 | −4.08 | 6150 | |
| 221616_s_at | TAF9L | −4.31 | 51616 | |
| 209463_s_at | TAF12 | −2.08 | 6883 | |
| 209152_s_at | TCF3 | −2.80 | 6929 | |
| 215167_at | CRSP2 | −3.18 | 9282 | |
| 204109_s_at | NFYA | −4.49 | 4800 | |
| 214766_s_at | AHCTF1 | −4.79 | 25909 | |
| 214918_at | HNRPM | −4.42 | 4670 | |
| 215152_at | MYB | −6.20 | 4602 | |
| 209511_at | POLR2F | −2.10 | 5435 | |
| 214144_at | POLR2D | −8.44 | 5433 | |
| 201026_at | EIF5B | −6.68 | 9669 | |
| 222294_s_at | EIF2C2 | −3.07 | 27161 | |
| 213087_s_at | EEF1D | −5.52 | 1936 | |
| 213907_at | EEF1E1 | −38.0 | 9521 | |
| 204906_at | RPS6KA2 | −49.2 | 6196 | |
| M | 208646_at | RPS14 | −2.30 | 6208 |
| 217559_at | RPL10L | −9.18 | 140801 | |
| 217266_at | RPL15 | −2.04 | 6138 | |
| 208903_at | RPS28 | −2.08 | 6234 | |
| 219762_s_at | RPL36 | −2.45 | 25873 | |
| 213897_s_at | MRPL23 | −3.74 | 6150 | |
| 212955_s_at | POLR2I | −2.03 | 5438 |
A negative value indicates downregulation in cells from DBA patients.
Abbreviations: E, bone marrow erythroid progenitor; M, myeloid progenitor; P, multipotential progenitor.