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. 2012 May 7;4:115–123. doi: 10.2147/CLEP.S30883

Table 3.

Crude and multivariable-adjusted 30-day and 1-year mortality according to combination of previously diagnosed cardiovascular comorbidities

Comorbidity combination n 30-day mortality 1-year mortality


Dead (n, %) Hazard ratio (95% CI) Dead (n, %) Hazard ratio (95% CI)
No comorbidity 202 19 (9.0) 1.00 330 (15.0) 1.00
Hypertension/diabetes 1173 136 (11.6) 1.09 (0.85–1.39) 270 (23.0) 1.27 (1.06–1.50)
Hypertension/heart failure 467 123 (26.5) 1.82 (1.41–2.34) 239 (51.4) 1.90 (1.58–2.29)
Hypertension/atrial fibrillation 233 35 (15.2) 1.16 (0.79–1.71) 73 (31.6) 1.21 (0.92–1.59)
Hypertension/stroke 224 47 (21.0) 1.73 (1.21–2.47) 84 (37.5) 1.76 (1.36–2.28)
Hypertension, diabetes, and heart failure 507 92 (18.2) 1.40 (1.06–1.85) 214 (42.3) 1.79 (1.48–2.16)
Hypertension, diabetes, and stroke 202 45 (22.2) 1.85 (1.30–2.62) 90 (44.6) 2.17 (1.69–2.79)
Other combinations 4573 732 (16.1) 1.31 (1.10–1.57) 1371 (30.1) 1.43 (1.35–1.63)

Notes: Cox proportional hazard regression model adjusted for age, sex, race, marital status, study year, type of acute myocardial infarction (Q wave versus non-Q wave) and acute hospital complications (atrial fibrillation, heart failure, cardiogenic shock). Comparisons are between patients with selected comorbidity clusters and patients without any comorbidity.