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Results of immunoassays demonstrating the modulation of serum adrenaline/noradrenaline levels and cAMP in blood cells of hamsters treated for 20 weeks with NNK. There was a 3.8-fold increase in noradrenaline and a 2.3-fold increase in adrenaline while cAMP was increased 2.2-fold. Data are mean values and standard errors of triplicate samples from the pooled blood of 10 hamsters per treatment group. Asterixes indicate values significantly (p<0.001) different from controls.
