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. Author manuscript; available in PMC: 2012 Jun 12.
Published in final edited form as: J Pathol. 2009 Aug;218(4):437–445. doi: 10.1002/path.2542

Figure 8.

Figure 8

Western blots, showing the induction of p-CREB and p-ERK1/2 in NNK-induced PDAC. Both phosphorylated proteins were barely detectable in control islet and duct cells. P-CREB was increased 2.65-fold (*: p<0.001) and p-ERK1/2 2.55-fold (*: p<0.001) over the levels observed in duct epithelial cells. Data in the graph are normalized (expression levels in duct cells=100%) mean values and standard errors of ratios of p-CREB over CREB and p-ERK1/2 over ERK1/2 from five densitometric readings per band. Each Western blot was conducted three times with similar data.