TABLE 2.
AIRWAY FUNCTION BY VEGF SNPs FOR YOUNG ADULTS
|
Z Scores of Adjusted FEV1/FVC Ratio* |
|||||||||
| TCRS Age 16 Years |
TCRS Age 22 Years |
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| VEGF-A SNPs | n | Mean | 95% CI | P | n | Mean | 95% CI | P | |
| rs3025028 | CC | 53 | 0.11 | −0.16 to 0.37 | 50 | 0.30 | 0.01 to 0.59 | ||
| CG | 122 | 0.05 | −0.12 to 0.22 | 112 | −0.03 | −0.20 to 0.14 | |||
| GG | 62 | −0.24 | −0.52 to 0.04 | 0.107 | 62 | −0.26 | −0.53 to −0.01 | 0.012 | |
| rs10434 | AA | 54 | 0.18 | −0.07 to 0.44 | 48 | 0.31 | 0.004 to 0.62 | ||
| AG | 115 | 0.09 | −0.10 to 0.27 | 107 | 0.02 | −0.16 to 0.20 | |||
| GG | 56 | −0.26 | −0.56 to 0.041 | 0.048 | 55 | −0.27 | −0.57 to −0.02 | 0.014 | |
Definition of abbreviations: CI = confidence interval; SNP = single-nucleotide polymorphism; TCRS = Tucson Children’s Respiratory Study; VEGF = vascular endothelial growth factor.
Adjusted for height and sex. P value is for analysis of variance model.