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. 2012 Jun 1;185(11):1190–1196. doi: 10.1164/rccm.201201-0088OC

TABLE 3.

CHANGES IN FORCED EXPIRATORY VOLUMES CAUSED BY HYPERVENTILATION OF HUMIDIFIED AIR AT HIGH TEMPERATURE AND AT ROOM TEMPERATURE

FEV1* (L)
FVC (L)
FEV1/FVC
Patient Type, Treatment Before During Before During Before During
Asthma
 RA 3.52 ± 0.29 3.44 ± 0.30 4.35 ± 0.46 4.43 ± 0.46 82.33 ± 3.24 78.67 ± 3.42*
 HA 3.45 ± 0.32 3.04 ± 0.21* 4.30 ± 0.46 4.29 ± 0.41 81.17 ± 2.94 71.67 ± 2.36*
Healthy
 RA 4.27 ± 0.32 4.44 ± 0.49 5.39 ± 0.65 5.31 ± 0.65 81.20 ± 4.41 81.60 ± 4.72
 HA 4.43 ± 0.48 4.48 ± 0.55 5.43 ± 0.72 5.43 ± 0.71 83.40 ± 4.37 83.40 ± 3.83

Definition of abbreviations: HA = humidified air at high temperature; RA = humidified air at room temperature.

*

Forced expiratory tests were performed before and at ∼8 min after the hyperventilation challenge in patients with asthma (n = 6) and healthy subjects (n = 5; the test was not done after HA in one subject).

Significant difference (P < 0.05; paired t test) between before and after the hyperventilation challenge.