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. 2012 Jun 4;2012:756358. doi: 10.1155/2012/756358

Figure 1.

Figure 1

Views of the Kv1.2-β 2 subunit complex. (a) Side view of the Kv1.2-β 2 structure with the extracellular solution above and the intracellular solution below. Four subunits of the channel are colored in yellow (T1 domain and voltage sensor) and green (pore). β subunit tetramer is colored in red. TM indicates the integral membrane component of the complex. (b) Stereoview of a single subunit of the channel and β subunit viewed from the side. Labels correspond to six transmembrane helices (S1 to S6). (c) View of the Kv1.2-β 2 structure from the extracellular side of the membrane. S1–S4 helices from each subunit form four surrounding voltage-sensing domains, S5-S6 regions (green) from the four subunits shape a single pore domain. Purple spheres are potassium ions. Images were generated using Protein Workshop Viewer 3.9 [15] and Protein Data Bank accession ID 2A79 [14].