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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Matrix Biol. 2012 Apr 16;31(5):285–289. doi: 10.1016/j.matbio.2012.03.003

Figure 3. Expression of the restin domain of type XV collagen does not suppress tumorigenicity of D98 AP2 cells in nude mice.

Figure 3

A. Kaplan-Meier plots of survival of mice injected with vector-only control clone (DP3), a clone expressing high levels of collagen XV (15:58), restin-only clones (Rest5, Rest2, Rest11), (log-rank tests: Rest5:DP3, P= 0.0584; Rest2:DP3, P=0.0018; Rest11:DP3, P=0.503; 15:58:DP3, P=0.0018; Rest5, Rest2, Rest11: 15:58, P<0.001). B. Western blot to show the expression levels of hcolXV and the restin domain in the clones at the time of injection, in comparison to tubulin. C. In vitro growth rates over 72 hours of clones used in A, DP3, 15:58, Rest2, Rest5, and Rest11.