BSE-SEM imaging of wild-type (A,B) and NBCe1-null (C,D) mice. Incisor teeth from 14-day-old NBCe1 null mice (Parts C and D) and an age-matched wild-type littermate (Parts A and B) were imaged in BSE-SEM using identical imaging parameters for both, which are defined in the text. Cross-sections are from an erupted, fully mature, region of the tooth. The enamel of the NBCe1-null mice is clearly hypomineralized. This is also evidenced by the color-coded images (Parts B andD), which illustrated marked differences in enamel mineralization for the NBCe1-null mice. Scale bars included.