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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Genet Epidemiol. 2011 Aug 4;35(7):620–631. doi: 10.1002/gepi.20610

Table iv.

Empirical Power in the presence of epistasis. The column labeled “LD” gives the R2 between the two causal SNPs. The results show that IBS kernel is useful for detecting epistasis.

Causal SNP 1 Causal SNP 2 LD IBS weighted IBS Linear min test
rs4377998 (untyped) rs6586684 (untyped) 0.392 0.538 0.532 0.122 0.102
rs4377998 (untyped) rs10112857 (typed) 0.539 0.588 0.588 0.168 0.18
rs1049874 (typed) rs6586684 (untyped) 0.563 0.574 0.548 0.122 0.11
rs1049874 (typed) rs10112857 (typed) 0.468 0.618 0.596 0.186 0.192

rs12541181 (untyped) rs2427746 (untyped) 0.422 0.926 0.914 0.688 0.766
rs12541181 (untyped) rs12155668 (typed) 0.461 0.94 0.918 0.668 0.738
rs7830490 (typed) rs2427746 (untyped) 0.409 0.928 0.916 0.704 0.764
rs7830490 (typed) rs12155668 (typed) 0.447 0.952 0.938 0.678 0.74