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. 2012 Jun 6;104(11):869–883. doi: 10.1093/jnci/djs035

Table 5.

Proportional hazard ratios on underlying cause lung cancer mortality for 15-year lagged REC cumulative exposure and average intensity for surface-only workers: quartiles, expanded categories, and continuous modeling results*

Analyses Results for quartiles, expanded categories, and continuous models for surface-only workers
Quartiles (78 LC deaths)
    Cumulative REC exposure (μg/m3-y)
        Exposure range 0 to <0.70 0.70 to <4.6 4.6 to <14 ≥14
        No. LC deaths 19 20 19 20
        REC HR (95% CI) 1.00 (referent) 1.28 (0.64 to 2.58) 0.73 (0.35 to 1.53) 1.00 (0.44 to 2.28)
        P .490 .407 .998
    Average REC intensity (μg/m3)
        Exposure range 0 to <0.57 0.57 to <0.91 0.91 to <1.4 ≥1.4
        No. LC deaths 19 18 21 20
        REC HR (95% CI) 1.00 (referent) 1.71 (0.82 to 3.58) 2.22 (1.01 to 4.90) 2.56 (1.09 to 6.03)
        P .154 .049 .031
Expanded categories (excluding <5 year tenure, 57 LC deaths)
    Cumulative REC exposure (μg/m3-y)
        Exposure range 0 to <20 20 to <40 40 to <80 ≥80
        No. LC deaths 44 7 4 2
        REC HR (95% CI) 1.00 (referent) 1.16 (0.46 to 2.94) 2.29 (0.60 to 8.75) 8.68 (1.61 to 46.90)
        P .756 .224 .012
    Average REC intensity (μg/m3)
        Exposure range 0 to <2 2 to <4 ≥4
        No. LC deaths 44 11 2
        REC HR (95% CI) 1.00 (referent) 2.33 (1.11 to 4.90) 4.63 (0.99 to 21.55)
        P .026 .051
Continuous models (excluding <5 y tenure)
    Cumulative REC exposure
        Exposure range Full Full
        Exposure units μg/m3-y Log μg/m3-y
        No. LC deaths 57 57
        REC HR (95% CI) 1.02 (1.00 to 1.03) 1.03 (0.75 to 1.42)
        P .026 .842
    Average REC intensity
        Exposure range Full Full
        Exposure units μg/m3 Log μg/m3
        No. LC deaths 57 57
        REC HR (95% CI) 1.42 (1.10 to 1.82) 2.60 (1.07 to 6.29)
        P .006 .034
*

CI = confidence interval; HR = hazard ratio; LC = lung cancer; REC = respirable elemental carbon; P = HR probability from two-sided χ2 Wald test. Workers categorized as surface-only until first going underground (if ever). Models adjusted for race/ethnicity, birth year, and sex; stratified by state.