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. 2012 Apr 5;21(13):2973–2990. doi: 10.1093/hmg/dds128

Figure 5.

Figure 5.

Aβ deposits in AβPP and MCAT/AβPP mice were assessed with the 6E10 monoclonal antibody. (A) Aβ deposits and quantification data in the 12-month-old AβPP and MCAT/AβPP mice. (B) Aβ deposits and quantification data in the 24-month-old AβPP and MCAT/AβPP mice. Images are with ×5 original magnification. The total number (upper) and size (bottom) of the Aβ plaques were significantly reduced in the 12- and 24-month-old MCAT/AβPP mice relative to the 12- and 24-month-old AβPP mice (*P < 0.01; four or five mice in each group).