Table 3.

mRNA fold changes of genes related to Aβ in 6-, 12- and 24-month-old MCAT/AβPP mice, relative to AβPP mice

Gene	mRNA fold change in 6-month-old MCAT/AβPP mice	mRNA fold change in 12-month-old MCAT/AβPP mice	mRNA fold change in 24-month-old MCAT/AβPP mice
Synaptophysin	5.3*	2.3*	4.3**
Catalase	5.4**	2.0*	2.1*
APP	−1.2	−2.3*	−1.7*
BACE1	−1.4	−1.8*	−1.9*
Neprilysin	4.3*	1.8*	1.9*
Insulin-degrading enzyme	1.7*	3.4**	1.9*
TTR	3.8**	2.2**	2.8**

*P ≤ 0.05.

**P ≤ 0.005.