TABLE 2.

Literature search results informing recommendations

Section	Topic	Studies informing recommendations, n (References)
I	Which populations are most appropriate for targeted testing of A1AT levels, to improve case-finding of patients at risk of or with documented lung disease associated with A1AT deficiency?	7 (20–26)
II	Is A1AT augmentation therapy effective in COPD patients with documented A1AT deficiency?	6 (11,33–36,38)

A1AT Alpha-1 antitrypsin; COPD Chronic obstructive pulmonary disease