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Role of ABCG2 knockdown in enhancing cytotoxic effects of anti-cancer drugs at 10 pM to 1 nM
| siRNA | % enhancement of chemosensitivity | ||||||||
|---|---|---|---|---|---|---|---|---|---|
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| ABCG2 | Doxorubicin | Paclitaxel | Cisplatin | ||||||
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| 10 pM | 100 pM | 1 nM | 10 pM | 100 pM | 1 nM | 10 pM | 100 pM | 1 nM | |
| 1 nM | 13% | 20% | 14% | 17% | 16% | 17% | 5% | 16% | 13% |
Abbreviation: siRNA, small interfering RNA.
