Table 4.

Role of ABCB1 knockdown in enhancing cytotoxic effects of anti-cancer drugs at 10 pM to 1 nM (doxorubicin and paclitaxel) and 100 pM to 10 nM (cisplatin)

siRNA	% enhancement of chemosensitivity
ABCB1	Doxorubicin			Paclitaxel			Cisplatin
	10 pM	100 pM	1 nM	10 pM	100 pM	1 nM	100 pM	1 nM	10 nM
1 nM	30%	18%	18%	27%	23%	26%	4%	10%	14%

Abbreviation: siRNA, small interfering RNA.