Table 7.

Scores for assessment of risk of bias for intervention studies

Risk of bias	Bertoglio et al. 2011	James et al. 2009	Adams et al. 2009	Rossignol et al. 2007	James et al. 2004
Randomisation	Uncertain	Open label	Uncertain	Open label	Open label
Concealment of allocation	Low risk	Open label	Low risk	Open label	Open label
Blinding	Low risk	Open label	Low risk	Open label	Open label
Incomplete outcome data	High risk	Low risk	High risk	Low risk	Low risk
Selective reporting	High risk	Low risk	High risk	Low risk	Low risk
Overall score	5	4	5	4	4

Scoring

Low risk = 2; Uncertain = 1; High risk/open label = 0