Table 7.
Associations of high socioeconomic position (compared to low) at four life stages with lymphocyte cell count (109/L) by sex, adjusted for agea, lifestyle factors and body mass index in 9,981 Chinese adults(≥50 years) from the Guangzhou Biobank Cohort Study, phase3, 2006-2008
| Women (n = 7,445) | Men (n = 2,536) | |||||
|---|---|---|---|---|---|---|
| Δ | 95% CI | AIC | Δ | 95% CI | AIC | |
| Critical period Modelb | ||||||
| Childhood | -0.03 | (-0.06, -0.01) | -8283 | 0.03 | (-0.02, 0.09) | -2438 |
| Early Adult | -0.08 | (-0.11, -0.05) | -8288 | 0.07 | (0.02, 0.13) | -2443 |
| Late Adult | -0.03 | (-0.06, 0.01) | -8278 | 0.05 | (0.00, 0.11) | -2440 |
| Current | -0.03 | (-0.06, -0.01) | -8281 | 0.03 | (-0.02, 0.09) | -2438 |
| Accumulation Modelc | -8284 | -2439 | ||||
| 0 | 0* | 0* | ||||
| 1 | -0.03 | (-0.08, 0.01) | 0.02 | (-0.06, 0.10) | ||
| 2 | -0.04 | (-0.08, 0.002) | 0.07 | (-0.01, 0.15) | ||
| 3 | -0.07 | (-0.12, -0.02) | 0.07 | (-0.02, 0.15) | ||
| 4 | -0.06 | (-0.12, -0.0003) | 0.13 | (0.02, 0.24) | ||
| Sensitive Periods Modeld | -8285 | -2440 | ||||
| Childhood | -0.02 | (-0.05, 0.01) | 0.02 | (-0.04, 0.08) | ||
| Early Adult | -0.04 | (-0.07, -0.01) | 0.06 | (0.002, 0.12) | ||
| Late Adult | 0.01 | (-0.03, 0.05) | 0.03 | (-0.03, 0.09) | ||
| Current | -0.01 | (-0.04, 0.02) | 0.00 | (-0.06, 0.06) | ||
| Fully Saturated Modele | -8274 | -2428 | ||||
Abbreviations: CI Confidence Interval; AIC Akaike Information Criterion
Bold numbers indicate P < 0.05 for coefficients or best fitting model for AICs
aAge in five year age groups. bEstimates for SEP at each individual life stage adjusted for age, smoking, alcohol use, and physical activity and body mass index but unadjusted for SEP at other life stages. cNumber of periods in high SEP adjusted for age, smoking, alcohol use, and physical activity and body mass index. dMutually adjusted for SEP at other life stages and adjusted for age, smoking, alcohol use, and physical activity and body mass index. eIncludes SEP at all four life stages and all possible interactions between all four measures of SEP. Also adjusted for age, smoking, alcohol use, and physical activity