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. 2012 Jun 12;7(6):e38390. doi: 10.1371/journal.pone.0038390

Figure 3. The frequency of GrB-producing CTLs from PBMCs cocultured with DC pulsed with epitope peptides.

Figure 3

The data was expressed as mean±SEM. The data from 5 subjects from every group was included. Triplicate wells from every peptide in the same experiment were used. The single peptides include 4 previously reported epitope peptides (E2 (723–731), NS3 (1073–1081), NS3 (1585–1593), and NS5b (2594–2602)), 7 predicted peptides and HLA-A2 restricted CTL HBV envelope epitope peptide (WLSLLVPFV) as an unrelated peptide control. The epitope peptide mixture (mix1∼mix14) contains 2 to 6 single epitopes in each mixture. A. GrB SFCs induced by single peptide in self-limited and chronic HCV infection. B. GrB SFCs induced by multiple epitope peptide mixtures in self-limited and chronic HCV infection; *P<0.05.