Table 2. Hepatitis C virus CTL epitopes prediction and identification.
Epitopes | Position | Sequence | The number of positive subjects | |
Self-limited(n) | Chronic infection (n) | |||
CTL-1△ | E2 (607–615) | CLVDYPYRL | 2/5* | 0 |
CTL-2△ | NS2 (838–846) | FLARLIWWL | 2/5 | 0 |
CTL-3△ | E2 (716–724) | WEYVLLLFL | 2/5 | 3/6 |
CTL-4△ | NS2 (834–842) | YYKVFLARL | 2/5 | 2/6 |
CTL-5△ | NS3 (1411–1419) | GLNAVAYYR | 2/5 | 2/6 |
CTL-6△ | NS4a (1700–1708) | VLYEAFDEM | 2/5 | 2/6 |
CTL-7△ | NS5b (2942–2950) | KYLFNWAVK | 3/5 | 2/6 |
CTL-8♦ | E2 (723–731) | FLLLADARV | 2/5 | 0 |
CTL-9♦ | NS3 (1073–1081) | CINGVCWTV | 3/5 | 3/5 |
CTL-10♦ | NS3 (1585–1593) | YLVAYQATV | 1/5 | 0 |
CTL-11♦ | NS5b (2594–2962) | ALYDVVTKL | 3/5 | 3/5 |
Note:△ stands for novel predicted epitopes.
stands for past reported epitopes.
means two positives in five subjects.