Table 2. Effect of Valacyclovir on Mean CD4 Count and Log₁₀ Plasma HIV-1 RNA Level.

		Placebo	Valacyclovir	Difference, adjusted*
	n	Mean (SD)	Mean (SD)	Mean	95% CI	P
CD4 count (cells/µl)
Enrollment	146	487 (174)	484 (179)	−3	−61, 55	0.92
6 months postpartum	116	612 (232)	631 (309)	17	−58, 93	0.72
12 months postpartum	136	565 (206)	638 (292)	73	6, 140	0.03
Log10 plasma HIV-1 RNA (copies/ml)
Enrollment	146	3.87 (0.83)	3.89 (0.95)	−0.01	−0.18, 0.17	0.95
6 months postpartum	136	4.40 (0.81)	3.98 (1.05)	−0.42	−0.65, −0.2	<0.001
12 months postpartum	136	4.53 (0.81)	4.10 (1.07)	−0.40	−0.63, −0.17	0.001

SD  =  standard deviation.

^*method used: Multivariate linear regression models control for baseline plasma HIV-1 RNA levels for plasma HIV-1 RNA models, and baseline CD4 for CD4 models.