Table 1. The content of CYP3A4 and CYP2B6 co-expressed with wild-type or six POR mutants in sf9 microsomal fractions were determined on the basis of reduced CO-difference spectrum.

Protein	CYP3A4 (pmol/mg protein)	CYP2B6 (pmol/mg protein)
WT	56.4±4.1	44.3±1.1
K49N	69.0±3.6	61.2±1.7
A115V	49.1±2.8	46.9±2.3
Y181D	74.1±6.7	49.2±4.5
S244C	48.3±2.0	36.8±1.8
A287P	59.5±3.3	54.5±3.8
G413S	43.9±2.1	56.9±1.9