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. 2012 Jun 12;6(6):e1692. doi: 10.1371/journal.pntd.0001692

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Bariami et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The analysis was performed on the significantly up-regulated genes found in CAYMAN and CUBA-DELTA compared to NO. The BLAST2GO software was used for the annotation, mapping and enrichment analysis. The figure represents all the significant GO-term categories found significantly enriched compared to the reference set (all transcripts present on the microarray) after a Fisher's exact test and Benjamini and Hochberg multiple testing correction (Pval<0.05). The test set percentage indicates the percentage of up regulated genes belonging to a GO term category compared to all up-regulated genes used in the GO-term analysis while the reference set percentage indicates the percentage of a particular GO-term category compared to all genes with GO-terms on the microarray.