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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2012 Apr 5;11(6):1320–1331. doi: 10.1158/1535-7163.MCT-11-0954

Figure 1.

Figure 1

Identification of Propachlor as a collaborating compound with Rad001. (A) 5000 compounds were added alone or together with 20nM Rad001 in C4-2 cells, the survival ratio gauged by ATP measurement between cells that are treated with single compound or combination with Rad001 is plotted. (B) The chemical structures of Rad001 and Propachlor. (C) Propachlor can collaborate with Rad001 to inhibit PC3 and C4-2 cells. Single compounds or combination with Rad001 were used to treat PC3 or C4-2 cells for 72 hrs followed by Celltiter Glo measurement to measure cell number. The two-way T-test showed P<0.05 between the two groups.