Fig. 1.

Rebound kinetics of LDL-cholesterol after lipid apheresis. The closed symbols are presenting the LDL lowering effect of lipid apheresis in patients with very high (> 500 mg/dl), high (250–499 mg/dl), and low (< 250 g/dl) but still elevated LDL-cholesterol serum concentrations and the reincrease of their individual LDL-cholesterol within two weeks. The LDL serum concentration before the next apheresis (weekly interval provided) is indicated by the open symbols. The sustaining LDL lowering effect one week after the first apheresis corresponds to the difference between the open and the closed symbols