Table 1.
Lipid levels before and after 6 weeks of treatment in two heterozygote patients with the p.W556R LDL receptor mutation
| Patients | Sex | Age (years) | TC (mmol/L) | TG (mmol/L) | LDL-C (mmol/L) | HDL-C (mmol/L) | LDLR (p.W556R) |
|---|---|---|---|---|---|---|---|
| No lipid-lowering therapy | M | 36 | 9.8 | 1.7 | 7.7 | 1.2 | Heteroz |
| Simvastatin 40 mg/ezetimibe 10 mg | 5.2 | 1.1 | 3.5 | 1.1 | |||
| No lipid-lowering therapy | F | 30 | 7.6 | 1.3 | 5.2 | 1.8 | Heteroz |
| Simvastatin 40 mg/ezetimibe 10 mg | 3.5 | 0.6 | 1.9 | 1.4 |
Age refers to years of age at blood sampling. Lipid values are given in millimoles/litre
F female; M male; TC total cholesterol; TG triglycerides; LDL-C LDL cholesterol; HDL-C HDL cholesterol; LDLR LDL receptor