Table 2.
Syndrome | Studies |
---|---|
Monogenic disorders other than CAPS and DIRA | |
Other diseases with IL-1 response | |
Familial Mediterranean fever (FMF) | [78,119]–[125] |
TNF receptor-associated periodic syndrome (TRAPS) | [126]–[129] |
Hyper immunoglobulin (Ig)D syndrome (HIDS) | [130,131] |
PAPA syndrome† | [132,133] |
Polygenic disorders‡ | |
SOJIA§ | [71,72,134] |
AOSD¶ | [135]–[141] |
PFAPA | [73] |
Behçet's disease | [77] |
Schnitzler syndrome | [74]–[76] |
‘Metabolic’ autoinflammatory diseases | |
Gout | [81]–[83] |
Diabetes type 2 | [84] |
Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome.
These probable polygenetic diseases do not yet have any genetic mutations or polymorphisms identified but are believed to be caused by genetic predispositions.
Only studies with more than 10 patients are listed.
Only studies with more than five patients are listed. DIRA: deficiency of the interleukin (IL)-1 receptor antagonist; CAPS: cryopyrin-associated periodic syndromes; PAPA: pyogenic arthritis, pyoderma gangrenosum and acne syndrome; FPAPA: periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis; SOJIA: systemic onset juvenile idiopathic arthritis; AOSD: adult-onset Still's disease; TNF: tumour necrosis factor.