. Author manuscript; available in PMC: 2012 Jun 13.

Published in final edited form as: Int J Sport Nutr Exerc Metab. 2011 Apr;21(2):146–154. doi: 10.1123/ijsnem.21.2.146

Table 2.

Individual Adverse Reactions With Oral Ingestion of N-Acetylcysteine Solution

Adverse reaction	Dose
Adverse reaction	0 mg/kg	35 mg/kg	70 mg/kg	140 mg/kg
Gastrointestinal
upset stomach	—	H¹, I¹	F¹, H¹, I²	A¹, C¹, D², E¹, I¹, J¹
nausea	—	—	—	C¹, H¹, J¹
stomach or intestinal gas	F¹, H¹	E¹, F¹	F¹, I³	A¹, C², D², F², I², J¹
Nongastrointestinal
sleepiness	A¹, D¹, H¹	D¹	B¹, C¹, D¹	F¹, I¹
metallic taste	J²	A¹	A¹, D¹, I¹	A¹, H¹, I¹, J¹
light-headedness	H¹	—	D¹	J¹
redness of eye, face, or hands	F¹	—	—	—
cough	—	—	D¹	—

Note. Uppercase letters (A–J) refer to individual subjects from Arm 2. Superscripts show ranked intensity of adverse reactions reported by each subject. Ranked intensities are (1) mild, (2) moderate, and (3) severe. Subjects who indicated “none” (0) for an adverse reaction are omitted for clarity. None of the subjects experienced welts or wheezing. See Table 1 for further details.