Table 3.
Proteins consistently of either higher or lower abundance in pancreatic fluid from chronic pancreatitis individuals with respect to chronic abdominal pain controls.
dye ratio (mean) |
abundance in CP |
protein name | IPI number | subcellular localization |
biological function |
spot #(s) |
---|---|---|---|---|---|---|
1.8866 | higher | Actin | IPI00021439 | cytoskeleton | structural | 21 |
1.5802 | higher | Alpha-1-antitrypsin | IPI00553177 | extracellular | protease inhibitor | 30, 31 |
1.4277 | higher | Desmoplakin | IPI00013933 | cytoskeleton | structural | 1 |
2.4658 | higher | SNC73 protein | IPI00386879 | extracellular | n/a | 16, 17 |
4.4735 | higher | TF Serotransferrin | IPI00022463 | extracellular | cell proliferation | 10, 12, 18 |
−3.2895 | lower | Arp2/3 complex 20 kDa subunit | IPI00554811 | cytoskeleton | structural | 64 |
−3.9172 | lower | Alpha-1-antichymotrypsin | IPI00550991 | extracellular | protease inhibitor | 26 |
−4.1582 | lower | Alpha-2-macroglobulin | IPI00478003 | extracellular | protease inhibitor | 59 |
−2.2757 | lower | Alpha-amylase 1 precursor | IPI00025476 | extracellular | enzyme | 56 |
−1.8589 | lower | Carboxypeptidase B | IPI00009826 | extracellular | enzyme | 54 |
−2.7721 | lower | Endoplasmin | IPI00027230 | endoplasmic reticulum | chaperone | 4 |
−2.1575 | lower | Glyceraldehyde-3-phosphate dehydrogenase | IPI00219018 | cytoplasm | metabolic enzyme | 34 |
−2.1418 | lower | Pancreatic triacylglycerol lipase | IPI00027720 | extracellular | enzyme | 53 |
−4.4010 | lower | Protein disulfide-isomerase | IPI00010796 | endoplasmic reticulum | enzyme | 25 |