TABLE 4.
Proportional hazards models of time to virologic rebound since suppression
Covariate |
Unadjusted |
Adjusted |
||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Female | 1.66 | 0.05–2.63 | 0.03 | |||
Recent immigrant | 1.36 | 0.86–2.15 | 0.19 | |||
Immigrant* sex | ||||||
Nonimmigrant and male | 1.00 | 1.0 | ||||
Immigrant and male | 1.28 | 0.66–2.49 | 0.46 | 1.27 | 0.65–2.47 | 0.49 |
Nonimmigrant and female | 1.82 | 0.91–3.61 | 0.09 | 1.93 | 0.96–3.86 | 0.06 |
Immigrant and female | 1.74 | 0.99–3.04 | 0.05 | 1.69 | 1.43–2.68 | 0.07 |
Age, per 10 years | 0.74 | 0.56–0.98 | 0.04 | |||
Male who has sex with men | 0.69 | 0.43–1.12 | 0.13 | |||
Injection drug user | 0.58 | 0.14–2.39 | 0.45 | |||
Coinfected with hepatitis C virus | 1.35 | 0.62–2.95 | 0.45 | |||
First HIV-positive test before 2000 | 1.00 | |||||
2000–2004 | 0.70 | 0.41–1.22 | 0.21 | |||
2005 or later | 0.38 | 0.16–0.93 | 0.03 | |||
Year of cART start | 0.99 | 0.88–1.10 | 0.81 | 0.95 | 0.85–1.06 | 0.32 |
NNRTI-based cART | 0.82 | 0.52–1.30 | 0.40 | |||
Viral load at cART start, per log10 copies/mL | 0.80 | 0.62–1.03 | 0.08 | |||
CD4 count at cART start, per 100 cells/mm3 | 1.28 | 1.14–1.44 | <0.0001 | 1.31 | 1.16–1.48 | <0.001 |
cART Combination antiretroviral therapy; NNRTI Non-nucleoside reverse-transcriptase inhibitors