Scheme 1.
Proposed Mechanism for SOR-Catalyzed Reduction of Superoxide via Hydroperoxo (T1) and Solvent-Bound Intermediates (T2)a
a In the absence of substrate or reducing equivalents the active site converts to the glutamate-bound resting (R).
Proposed Mechanism for SOR-Catalyzed Reduction of Superoxide via Hydroperoxo (T1) and Solvent-Bound Intermediates (T2)a
a In the absence of substrate or reducing equivalents the active site converts to the glutamate-bound resting (R).