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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Clin Lipidol. 2012 Apr 1;7(2):141–149. doi: 10.2217/clp.12.6

Table 1.

Guidelines for lipid management in peripheral arterial disease.

Guideline source Year LDL-C HDL-C Triglycerides Ref.
ACCF/AHA 2011 Class 1: LDL <100 mg/dl, for all patients with PAD using HMG-CoA reductase inhibitor (statin)
Class 2a: LDL <70 mg/dl, for those at high risk of ischemic events
Class 2a: low HDL, consider treatment with fibric acid derivative Class 2a: elevated triglycerides, consider treatment with fibric acid derivative [28]
TASC II 2007 LOE A: LDL <100 mg/dl, for all patients with PAD
LOE B: LDL <70 mg/dl, for patients with atherosclerosis in other territories
LOE A: statin drugs should be the primary agent used
LOE B: low HDL, consider treatment with niacin or fibrates LOE B: elevated triglycerides, consider treatment with fibrates [27]
ESC 2011 Class 1: LDL <2.5 mmol/l (100 mg/dl), for all patients with PAD
Class 1: Optimal LDL <1.8 mmol/l (<70 mg/dl)
Class 1: Goal >50% LDL reduction, if target level cannot be reached
Not addressed in guidelines Not addressed in guidelines [29]

ACCF: American College of Cardiology Foundation; AHA: American Heart Association; ESC: European Society of Cardiology; LOE: Level of evidence; PAD: Peripheral arterial disease; TASC II: Inter-Society Consensus for the Management of Peripheral Arterial Disease.