Table 1.
Guideline source | Year | LDL-C | HDL-C | Triglycerides | Ref. |
---|---|---|---|---|---|
ACCF/AHA | 2011 | Class 1: LDL <100 mg/dl, for all patients with PAD using HMG-CoA reductase inhibitor (statin) Class 2a: LDL <70 mg/dl, for those at high risk of ischemic events |
Class 2a: low HDL, consider treatment with fibric acid derivative | Class 2a: elevated triglycerides, consider treatment with fibric acid derivative | [28] |
TASC II | 2007 | LOE A: LDL <100 mg/dl, for all patients with PAD LOE B: LDL <70 mg/dl, for patients with atherosclerosis in other territories LOE A: statin drugs should be the primary agent used |
LOE B: low HDL, consider treatment with niacin or fibrates | LOE B: elevated triglycerides, consider treatment with fibrates | [27] |
ESC | 2011 | Class 1: LDL <2.5 mmol/l (100 mg/dl), for all patients with PAD Class 1: Optimal LDL <1.8 mmol/l (<70 mg/dl) Class 1: Goal >50% LDL reduction, if target level cannot be reached |
Not addressed in guidelines | Not addressed in guidelines | [29] |
ACCF: American College of Cardiology Foundation; AHA: American Heart Association; ESC: European Society of Cardiology; LOE: Level of evidence; PAD: Peripheral arterial disease; TASC II: Inter-Society Consensus for the Management of Peripheral Arterial Disease.